NORMAL

CEP 8 SpectrumOrange hybridized to a normal cell showing two orange signals indicating two copies of chromosome 8. In a normal cell, the expected pattern for a nucleus hybridized with the CEP 8 probe is a two orange (2O) signal pattern. In an abnormal cell containing trisomy 8, the expected pattern will be a three orange (3O) signal pattern.

NORMAL

LSI IGH/MYC/CEP 8 Tri-Color Dual Fusion Probes hybridized to a normal nucleus showing the expected 202G2A signal pattern.

ABNORMAL

LSI MYC Dual Color Break Apart Rearrangement Probe hybridized to an abnormal nucleus showing a one orange, one green and one orange/green fusion (1O1G1F) signal pattern.A normal nucleus hybridized with the LSI MYC Dual Color Break Apart Rearrangement Probe produces a two orange/green (yellow) fusion (2F) pattern. A one orange, one green, and one fusion pattern (1O1G1F) is expected from a sample with a t(2;8), t(8;22) or t(8;14) having a breakpoint within the gap between the hybridization targets of the LSI MYC probes.

NORMAL

LSI C-MYC Probe hybridized to a cell. Multiple orange signals are visible.

NORMAL

NORMAL

LSI AML1/ETO Dual Color, Dual Fusion Translocation Probe hybridized to a nucleus showing a one orange, one green and two fusion (1O1G2F) signal pattern.